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Paratesticular Embryonal Rhabdomyosarcoma (RMSE-PT): A Case Study in the Surgery Department of the Regional Hospital of Ziguinchor (Senegal)

Received: 5 May 2022     Accepted: 24 May 2022     Published: 9 June 2022
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Abstract

Introduction: Paratesticular embryonal rhabdomyosarcoma (RMSE-PT) is a rare and aggressive malignant mesenchymal tumor developed at the expense of connective tissue, representing approximately 7% of all rhabdomyosarcomas. Embryonic and alveolar histological types are most common in children, the pleomorphic type occurs exclusively in adults, and the prognosis is poor. The treatment method consists of tumor resection surgery, radiotherapy, and/or adjuvant chemotherapy. Here, we report a case of paratesticular embryonal rhabdomyosarcoma in a 3-year-old child. Through this observation, we discuss the diagnostic and therapeutic. Methods: In this report, our patient was a 3-year-old child with a large, painless right purse that had evolved over four months and was gradually increasing in volume. Physical examination detected a right scrotal mass, hard, painless, necrotic, suggestive of gangrene, while the left testicle was palpated at the bottom of the bursa, of normal appearance. The diagnosis revealed scrotal gangrene. Results: During the surgery, a large inguinoscrotal tumor was realized, and the realization of a right orchidectomy by the scrotal way with complete excision and dissection of an inguinal lymph node was finally made. The tumor markers (beta-human chorionic gonadotropin and alpha-fetoprotein) were negative, except for lactate dehydrogenase (LDH), which was increased. The surgical specimen's immunohistochemistry revealed an embryonic rhabdomyosarcoma invading the spermatic cord. The ultrasound revealed a tumor mass in the right testis. Computed tomography performed one month after surgery was normal. Conclusions: The care is multidisciplinary, combining surgery, polychemotherapy, and radiotherapy. The rarity of the clinical and the delay in diagnosis were the aggravating factors in the prognosis of our patient.

Published in International Journal of Clinical Urology (Volume 6, Issue 1)
DOI 10.11648/j.ijcu.20220601.24
Page(s) 63-65
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Rhabdomyosarcoma, Paratesticular, Surgery, Chemotherapy, Radiotherapy

References
[1] Boris Amougou, Divine Eyongeta, Jean Paul et al. Rhabdomyosarcome paratesticulaire: à propos d’un cas et révue de la littérature [Paratesticular rhabdomysarcoma: about a case and litterature review]. PAMJ-39 (71). 26 May 2021.
[2] El Mahdi Graiouid, Chakir Y, Gallouo M, et al. Rhabdomyosarcome paratesticulaire: à propos d’un cas [Paratesticular rhabdomyosarcoma: about a case] The Pan African Medical Journal, 2019. 33.
[3] Bognon Gilles, Akodjenou Joseph, Guédénon Medard, et al. Paratesticular Rhabdomyosarcoma in 30 Months Old Child at the Lagoon Mother and Child Teaching Hospital (CHUMEL) in Cotonou. Open Journal of Pediatrics, 2022, 12, 245-251 https://www.scirp.org/journal/ojped
[4] Han kun Ng, Shankaran Thevarajah, Ann Feng Pan. Paratesticular spindle cell rhabdomyosarcoma: A case report of a rare tumor. Pediatr Urol Case Rep 2020; 7 (4): 107-111 https://www.pediatricurologycasereports.com
[5] Ahsaini, M., Mellouki A, Ouattar K et al. Un traumatisme scrotal négligé révélant un rhabdomyosarcome embryonnaire para-testiculaire: à propos d’un cas [Neglected scrotal trauma revealing paratestic embryonic rhabdomyosarcoma: about a case]. The Pan African Medical Journal, 2018. 30.
[6] Wu, H.-Y., H. M. Snyder III, and R. B. Womer, Genitourinary rhabdomyosarcoma: which treatment, how much, and when? Journal of pediatric urology, 2009. 5 (6): p. 501-506.
[7] Sutow W, Sullivan MP, Ried HL, et al., Prognosis in childhood rhabdomyosarcoma. Cancer, 1970. 25 (6): p. 1384-1390.
[8] Sow O, Sarr A, Ndiaye M et al., Rhabdomyosarcome paratesticulaire: à propos d´un cas chez un adulte jeune [Paratesticular rhabdomysarcoma: about a case in a young adult]. PAMJ-Clinical Medicine, 2021. 5 (34).
[9] Keskin, S., Moudouni S, Koutani A, et al. Clinicopathological characteristics and treatment outcomes of adult patients with paratesticular rhabdomyosarcoma (PRMS): A 10-year single-center experience. Canadian Urological Association Journal, 2012. 6 (1): p. 42.
[10] Tazi, K, Moudouni S, Koutani A et al. Rhabdomyosarcome paratesticulaire de l’adulte jeune [Paratesticular rhabdomysarcoma of young adults]. Prog Urol, 2000. 10 (3): p. 469-72.
[11] Nesa, S, Lefebvre Y, Montfort J et al., Rhabdomyosarcome paratesticulaire: à propos d'un cas [Paratesticular rhabdomysarcoma: about a case]. Acta urologica belgica, 1994. 62: p. 37.
[12] Mhiri, M., Sellami F, Sellami M et al. Les tumeurs malignes para-testiculaires: à propos de trois cas rares [Paratestic malignant tumors: about three rare cases]. La Semaine des hôpitaux de Paris, 1989. 65 (43-44): p. 2652-2655.
[13] Lopez Lopez C, Nova Sanchez E, Fernandez Puentes JC, et al. Hydrocele as the first manifestation of paratesticular rhabdomyosarcoma. Archivos Espanoles de Urologia, 1990. 43 (3): p. 288-291.
[14] Dangle, P. P, Correa A, Tennyson L, et al. Current management of paratesticular rhabdomyosarcoma. in Urologic Oncology: Seminars and Original Investigations. 2016. Elsevier.
[15] Seitz G, Dantonello TM, Kosztyla D, et al. Impact of hemiscrotectomy on the outcome of patients with embryonal paratesticular rhabdomyosarcoma: results from the Cooperative Soft Tissue Sarcoma Group Studies CWS-86, 91, 96 and 2002P. The Journal of urology, 2014. 192 (3): p. 902-907.
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  • APA Style

    Thierno Amadou Oury Sow, Samba Thiapato Faye, Mory Sangaré, Mohamed Habiboulah Moustapha Ova, Ibrahima Diallo, et al. (2022). Paratesticular Embryonal Rhabdomyosarcoma (RMSE-PT): A Case Study in the Surgery Department of the Regional Hospital of Ziguinchor (Senegal). International Journal of Clinical Urology, 6(1), 63-65. https://doi.org/10.11648/j.ijcu.20220601.24

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    ACS Style

    Thierno Amadou Oury Sow; Samba Thiapato Faye; Mory Sangaré; Mohamed Habiboulah Moustapha Ova; Ibrahima Diallo, et al. Paratesticular Embryonal Rhabdomyosarcoma (RMSE-PT): A Case Study in the Surgery Department of the Regional Hospital of Ziguinchor (Senegal). Int. J. Clin. Urol. 2022, 6(1), 63-65. doi: 10.11648/j.ijcu.20220601.24

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    AMA Style

    Thierno Amadou Oury Sow, Samba Thiapato Faye, Mory Sangaré, Mohamed Habiboulah Moustapha Ova, Ibrahima Diallo, et al. Paratesticular Embryonal Rhabdomyosarcoma (RMSE-PT): A Case Study in the Surgery Department of the Regional Hospital of Ziguinchor (Senegal). Int J Clin Urol. 2022;6(1):63-65. doi: 10.11648/j.ijcu.20220601.24

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  • @article{10.11648/j.ijcu.20220601.24,
      author = {Thierno Amadou Oury Sow and Samba Thiapato Faye and Mory Sangaré and Mohamed Habiboulah Moustapha Ova and Ibrahima Diallo and Abdoulaye Sadjo Diallo and Alhassane Ismael Touré and Cheikh Diouf},
      title = {Paratesticular Embryonal Rhabdomyosarcoma (RMSE-PT): A Case Study in the Surgery Department of the Regional Hospital of Ziguinchor (Senegal)},
      journal = {International Journal of Clinical Urology},
      volume = {6},
      number = {1},
      pages = {63-65},
      doi = {10.11648/j.ijcu.20220601.24},
      url = {https://doi.org/10.11648/j.ijcu.20220601.24},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20220601.24},
      abstract = {Introduction: Paratesticular embryonal rhabdomyosarcoma (RMSE-PT) is a rare and aggressive malignant mesenchymal tumor developed at the expense of connective tissue, representing approximately 7% of all rhabdomyosarcomas. Embryonic and alveolar histological types are most common in children, the pleomorphic type occurs exclusively in adults, and the prognosis is poor. The treatment method consists of tumor resection surgery, radiotherapy, and/or adjuvant chemotherapy. Here, we report a case of paratesticular embryonal rhabdomyosarcoma in a 3-year-old child. Through this observation, we discuss the diagnostic and therapeutic. Methods: In this report, our patient was a 3-year-old child with a large, painless right purse that had evolved over four months and was gradually increasing in volume. Physical examination detected a right scrotal mass, hard, painless, necrotic, suggestive of gangrene, while the left testicle was palpated at the bottom of the bursa, of normal appearance. The diagnosis revealed scrotal gangrene. Results: During the surgery, a large inguinoscrotal tumor was realized, and the realization of a right orchidectomy by the scrotal way with complete excision and dissection of an inguinal lymph node was finally made. The tumor markers (beta-human chorionic gonadotropin and alpha-fetoprotein) were negative, except for lactate dehydrogenase (LDH), which was increased. The surgical specimen's immunohistochemistry revealed an embryonic rhabdomyosarcoma invading the spermatic cord. The ultrasound revealed a tumor mass in the right testis. Computed tomography performed one month after surgery was normal. Conclusions: The care is multidisciplinary, combining surgery, polychemotherapy, and radiotherapy. The rarity of the clinical and the delay in diagnosis were the aggravating factors in the prognosis of our patient.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Paratesticular Embryonal Rhabdomyosarcoma (RMSE-PT): A Case Study in the Surgery Department of the Regional Hospital of Ziguinchor (Senegal)
    AU  - Thierno Amadou Oury Sow
    AU  - Samba Thiapato Faye
    AU  - Mory Sangaré
    AU  - Mohamed Habiboulah Moustapha Ova
    AU  - Ibrahima Diallo
    AU  - Abdoulaye Sadjo Diallo
    AU  - Alhassane Ismael Touré
    AU  - Cheikh Diouf
    Y1  - 2022/06/09
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ijcu.20220601.24
    DO  - 10.11648/j.ijcu.20220601.24
    T2  - International Journal of Clinical Urology
    JF  - International Journal of Clinical Urology
    JO  - International Journal of Clinical Urology
    SP  - 63
    EP  - 65
    PB  - Science Publishing Group
    SN  - 2640-1355
    UR  - https://doi.org/10.11648/j.ijcu.20220601.24
    AB  - Introduction: Paratesticular embryonal rhabdomyosarcoma (RMSE-PT) is a rare and aggressive malignant mesenchymal tumor developed at the expense of connective tissue, representing approximately 7% of all rhabdomyosarcomas. Embryonic and alveolar histological types are most common in children, the pleomorphic type occurs exclusively in adults, and the prognosis is poor. The treatment method consists of tumor resection surgery, radiotherapy, and/or adjuvant chemotherapy. Here, we report a case of paratesticular embryonal rhabdomyosarcoma in a 3-year-old child. Through this observation, we discuss the diagnostic and therapeutic. Methods: In this report, our patient was a 3-year-old child with a large, painless right purse that had evolved over four months and was gradually increasing in volume. Physical examination detected a right scrotal mass, hard, painless, necrotic, suggestive of gangrene, while the left testicle was palpated at the bottom of the bursa, of normal appearance. The diagnosis revealed scrotal gangrene. Results: During the surgery, a large inguinoscrotal tumor was realized, and the realization of a right orchidectomy by the scrotal way with complete excision and dissection of an inguinal lymph node was finally made. The tumor markers (beta-human chorionic gonadotropin and alpha-fetoprotein) were negative, except for lactate dehydrogenase (LDH), which was increased. The surgical specimen's immunohistochemistry revealed an embryonic rhabdomyosarcoma invading the spermatic cord. The ultrasound revealed a tumor mass in the right testis. Computed tomography performed one month after surgery was normal. Conclusions: The care is multidisciplinary, combining surgery, polychemotherapy, and radiotherapy. The rarity of the clinical and the delay in diagnosis were the aggravating factors in the prognosis of our patient.
    VL  - 6
    IS  - 1
    ER  - 

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Author Information
  • Surgery Department, Regional Hospital of Ziguinchor, Cheikh Anta Diop University of Dakar, Ziguinchor, Senegal

  • Department of Urology-Andrology, Principal Hospital of Dakar, Cheikh Anta Diop University of Dakar, Dakar, Senegal

  • Surgery Department, Regional Hospital of Ziguinchor, Cheikh Anta Diop University of Dakar, Ziguinchor, Senegal

  • Department of Urology-Andrology, Principal Hospital of Dakar, Cheikh Anta Diop University of Dakar, Dakar, Senegal

  • Surgery Department, Regional Hospital of Ziguinchor, Cheikh Anta Diop University of Dakar, Ziguinchor, Senegal

  • Pathology Anatomy Department, Aristide Le Dantec Hospital, Cheikh Anta Diop University of Dakar, Dakar, Senegal

  • Surgery Department, Regional Hospital of Fatick, Cheikh Anta Diop University of Dakar, Fatick, Senegal

  • Surgery Department, Regional Hospital of Ziguinchor, Cheikh Anta Diop University of Dakar, Ziguinchor, Senegal

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